Pdk1 Antibody

PDK1 inhbits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit thus contributing to the regulation of glucose metabolism. PDK1 Antibodies Antibodies that detect PDK1 can be used in several scientific applications including Western Blot Immunocytochemistry Immunohistochemistry Paraffin Immunoprecipitation and ELISA.

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View detailed PDK1 antibody specifications by linking to the specific product blocks.

Pdk1 antibody. Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser241 of human PDK1. PDK1 Proteins Antibodies cDNA Clones Research Reagents PDK1 Pyruvate Dehydrogenase Kinase 1 is a protein coding gene located on human chromosome 2q311. Anti-PDK1 antibody EPR19573 ab207450 Research with confidence consistent and reproducible results with every batch Long-term and scalable supply powered by recombinant technology for fast production Success from the first experiment confirmed specificity through extensive validation.

PDK1 pyruvate dehydrogenase kinase isoform 1 is also named as PDHK1 and belongs to the PDKBCKDK protein kinase family. PDK1 pyruvate dehydrogenase kinase isoform 1 is also named as PDHK1 and belongs to the PDKBCKDK protein kinase family. PDPK1 3 Phosphoinositide Dependent Protein Kinase 1 phosphorylates AGC kinases.

Select appropriate PDK1 antibodies for your research by isotype epitope applications and species reactivity. SpecificityThe antibody detects endogenous level of PDK1 only when phosphorylated at serine 241. Santa Cruz Biotechnology Inc.

It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit thus contributing to the regulation of glucose metabolism PMID17683942. Validated in WB IHC Flow Cyt ICCIF and tested in Mouse Rat Human African green monkey. PDK1 Antibody E-10 is a mouse monoclonal IgM kappa light chain provided at 200 µgml specific for an epitope mapping between amino acids 410-436 at the C-terminus of PDK1 of human origin recommended for detection of precursor and mature PDK1 of mouse rat and human origin by WB IP IF.

PDK1 antibodies are useful tools for glucose metabolism research and mitochondrial metabolism studies. Phospho-PDK1 Y9 antibody Polyclonal 1 mgml. Mouse monoclonal PDK1 antibody 4A11.

This target gene encodes the protein pyruvate dehydrogenase kinase 1 in humans and may also be known as pyruvate dehydrogenase kinase isozyme 1 and Pyruvate dehydrogenase acetyl-transferring kinase isozyme 1 mitochondrial. Rabbit anti PDK1 pSer241 antibody recognizes PDK1 also known as 3-phosphoinositide-dependent protein kinase 1 or PDPK1 when phosphorylated at serine 241. PDPK1 also phosphorylates Protein Kinase B PKB at threonine 308 in the presence of phosphatidylinositol-345-trisphosphate.

PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. Antibodies are purified by protein A and peptide affinity chromatography. PDK1 is a master kinase involved in numerous cell processes including proliferation differentiation and cell survival.

It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit thus contributing to the regulation of glucose metabolism PMID17683942. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the carboxy terminus of human PDK1. Anti-PDK1 antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies affinity isolated antibody buffered aqueous glycerol solution HPA027376 Anti-PDK1 antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies affinity isolated antibody buffered aqueous glycerol solution.

Antibodies are purified by protein A and peptide affinity chromatography. PDK-1 activates conventional PKC and PKCz zeta through phosphorylation of critical threonine residues in the activation loop. PDK-1 also phosphorylates Protein Kinase B PKB at threonine 308 in the presence of phosphatidylinositol-345-trisphosphate.

Offers a broad range of PDK1 antibodies. Cited in 31 publications. Select PDK1 antibodies from monoclonal antibodies listed below.

The human PDK1 gene encodes a 49244 Da protein containing 436 amino acids. The PDK1 protein is ubiquitously expressed in heart adrenal and other tissues. PDK-1 3-Phosphoinositide-Dependant Protein Kinase-1 phosphorylates AGC kinases.

Antibody information for antibodies HPA027376 and CAB017554 used in analysis of ENSG00000152256 PDK1. Anti-PDK1 antibodies are offered by a number of suppliers.

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